The phrase "a significant assay" is correct and usable in written English.
It can be used in scientific or research contexts to refer to an assay that has considerable importance or impact in a study or experiment.
Example: "The researchers conducted a significant assay to determine the effectiveness of the new drug on cancer cells."
Alternatives: "an important assay" or "a notable assay".
The addition of a third primer to the oligonucleotide mix that perfectly matches the H1N1v sequences yielded a significant improve in assay performance with H1N1v viruses without reducing the performance on the other subtypes H1N1, H3N2 and H5N1.
This approach also eliminates template source-based variation in PCR amplification, a significant cause of assay nonlinearity.
Reagents can have a significant effect on assay reproducibility [ 27] due to some parameters such as different polymerases sensitivity [ 28], primer binding efficiency and the concentration of Mg2+ [ 29].
The results obtained demonstrate that the current HTS-assay represents a significant improvement over previous assays, with a higher turnover of MAMC and a higher selectivity for CYP2D6.
Neither drug had a significant effect in assays against controls (no drug) in the absence of sleep manipulations.
A recent meta-analysis of LINE-1 methylation and bladder cancer found a significant heterogeneity in assays used to quantify methylation (Woo and Kim, 2012).
This assay provides a significant improvement from previously described Sequential ChIP assays [ 57- 60] and it differs from those in two main aspects.
We then selected the compounds with a significant cytotoxicity for apoptosis assay.
Also by this assay, a significant increase of PTGDS was observed in all MOH abusers, according to 2-DE and Western blot results.
Pearson correlation showed a significant correlation between our assay and the mass-spec method (Pearson correlation: 0.863, p = 0.027) (Fig. 5).
