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The phrase "a significant and severe" is correct and usable in written English.
It can be used to describe something that is both important and serious in nature, often in contexts such as reports, analyses, or discussions of issues.
Example: "The study revealed a significant and severe impact on the local ecosystem due to pollution."
Alternatives: "a major and critical" or "a considerable and grave".
Exact(1)
However, in MHS animals SCh alone caused a significant and severe decrease in pH and BE and a relevant increase of PaCO2 and serum lactate.
Similar(59)
We found a significant and consistent association between severe hyperchloremia and mortality in a large ICU population, confirming on a broader scale previous findings after non-cardiac surgery and sepsis [1, 2].
To that end, the European Union recently finalized the text of what looks to be the world's single most significant — and severe — data privacy law to date.
Stages 2 and 3 are considered significant and severe fibrosis respectively.
The terms "significant" and "severe" are used interchangeably in this paper when referring to the column damage.
Significant and severe recent weight losses were detected in 7% and 5% of patients respectively.
The homozygote however has a significant protection against severe malaria (including severe malarial anaemia) and severe non-malarial illnesses[54].
Over the past few decades, EV71 epidemics have occurred in various countries and caused a significant proportion of severe complications and deaths in children, particularly in the Asia-Pacific region.
Thirty-nine percent of participants had severe immunosuppression (CD4 cell count < 200), and univariate and multivariate logistic regression showed a significant association between severe immunodepression and depressive symptoms.
The relationship between migraine and sleep has been reported, and there was a significant association between severe sleep disturbance and primary headache disorder, especially in CM [32].
Logistic regression on a model containing DM status, race/ethnicity, and age resulted in a significant association between severe coccidioidomycosis and DM (OR = 3.2, CI = 1.8 5.8) (Table 4).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com