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Tracking a fund's portfolio through regulatory filings may not be a scintillating way to spend an evening, but it can indicate when a manager has made a significant and possibly perilous shift in an investment approach.
It's quite a significant and possibly worrying development.
Given the severity of the toxicities it would have been a significant (and possibly unethical) burden for patients to complete HRQL questionnaires.
We envision that such environmental modulation of channel properties plays a significant and possibly adaptive role in tuning channel kinetics in response to temperature.
While the approach of Dinh, Rosner et al. could result in faster identification of families with Lynch syndrome than reflex testing of CRC patients, it would also entail a significant and possibly disruptive burden on primary care when initiated, which also may not have been costed in their analysis.
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Of course the results need to be verified and reproduced elsewhere, since "extraordinary claims require extraordinary evidence", but I still believe this is a hugely significant – and possibly Nobel prize-worthy – discovery.
Physical and psychological problems after childbirth are common, and may have a significant negative and possibly long-term impact on women's wellbeing and daily functioning [ 1].
With the economy in a significant downturn, and possibly a recession, some had feared a repeat of 1970s-style stagflation.
This is a significant development and possibly Nokia's best bet for actually connecting with the young users it so hopes to court.
The count of motif AP1F had a significant, positive and possibly linear effect on the average expression in a subspace of the second eigensystem, both in the MCAO (p = 0.0019, R 2 = 0.64) and in the kainate dataset.
No matter how much muscle Senate Democrats may put behind enacting a public option, the policy faces significant and possibly insurmountable obstacles in the near term.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com