In the near past, South Africa's health worker shortages as a result of emigration were viewed as significant and harmful.
Dietary fat recommendations are a case in point, because they may have led to significant and harmful unintended consequences.
The string of adjectives was meant to be chilling: "large and arbitrary," "severe," "significant and harmful," "very significant," "blunt," "mindless" and "extraordinarily troublesome".
"Replacing the unnecessary automatic budget cuts, known as sequester, which caused significant and harmful damage to schools and working families, with smart investments in education, infrastructure, and research and development is necessary to move the country forward".
"Placing more police in schools has significant and harmful unintended consequences for young people that must be considered before agreeing to any proposal that would increase the presence of law enforcement in schools,"says an issue brief released Friday by the Advancement Project, Dignity in Schools and other organizations.
A major limitation to the systemic use of drugs acting on adenosine receptors is represented by their wide distribution, especially in the CNS and in the cardiovascular system, which could account for significant and harmful side effects.
Such a result clearly suggests that initial pulmonary hyperinflation is the prelude to secondary lung distortion and bronchial damage, and that early ventilator-induced hyper-inflation has a significant secondary harmful impact.
Some behavior that seems to affect only oneself, e.g., taking recreational drugs, may have a significant indirect harmful effect on others by supporting the illegal and harmful activity of those gangs that benefit from the sale of those drugs.
Bovine ephemeral fever virus (BEFV), identified as the causative pathogen of bovine ephemeral fever (BEF), is responsible for increasing numbers of epidemics/outbreaks and has a significant harmful effect on the livestock industry.
