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The phrase "a significant amount of interaction" is correct and usable in written English.
It can be used when discussing the level or extent of engagement or communication between individuals or groups.
Example: "The study revealed that there was a significant amount of interaction between the participants during the group activities."
Alternatives: "a considerable level of interaction" or "a substantial degree of interaction."
Exact(1)
Patients with active foot disease and lower limb amputations due to diabetes have a significant amount of interaction with the health care services.
Similar(57)
A significant amount of protein interaction data has been generated for Arabidopsis, but the interactions have been produced using different analysis methods and stored in different databases (12).
However, the wiki activities need to be well-designed and monitored to ensure that there is a significant amount of this interaction with good quality.
The effect is more pronounced when a significant amount of hydrophilic interaction is present.
The Biomolecular Interaction Network Database BINDD) is a major source of curated biomolecular interactions, which has been unmaintained for the last few years, a trend which will eventually result in the loss of a significant amount of unique biomolecular interaction information, mostly as database identifiers become out of date.
Each student in this course attended either a morning or afternoon 1-h lecture of ∼90 students four times a week and attended one of eight student labs of ∼24 students each, which met once a week for 3 h and 20 min. This course used a heavy regimen of active learning, including a significant amount of guided student student interaction in both lecture and lab.
This level of performance suggests that AAC alone can capture a significant amount of information required for interaction prediction.
The female seems to choose the male she mates with, and the males compete for the attention of the female with a significant amount of vocalization and antagonistic interactions.
A significant amount of data on nanomaterial biological interactions exists; however, no consensus has been gained on the appropriate test methods (assays) to evaluate biological effect or toxicity, on the relative influence that physicochemical properties have on nanoparticle effects, or on the fundamental principles that govern nano/biointeractions.
With 2,362,352 monthly active users, the site's Facebook app sees significant amount of interaction with the site's social network and and also helps pull in friends on the website and vice versa.
A significant amount of research has been focused on the interactions of aspirin with proteins.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com