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The phrase "a significant amount is" is correct and usable in written English.
It can be used when discussing quantities or degrees of something, often in a formal or academic context.
Example: "A significant amount is required to complete the project successfully."
Alternatives: "a considerable quantity is" or "a substantial amount is".
Exact(13)
But a significant amount is in foreign hands.
As a result, a significant amount is known about their general cell biological and biochemical effects.
"A significant amount is consumed by intaking and discharging large amounts of air into and from the lung by agitating the diaphragm.
But a significant amount is left over for the local community, which supplies the labor and, in an increasing number of cases, grows foodstuffs for the camps.
Most of the state's electrical power is generated in coal-burning plants, although a significant amount is produced in the state's three nuclear facilities.
Such regulations shall require such organizations to make distributions of a percentage of either income or assets to supported organizations (as defined in section 509(f)(3) of such Code) in order to ensure that a significant amount is paid to such organizations.
Similar(47)
Only four Badgers expected to play a significant amount were suspended.
Of course, not everyone who voted leave was racist, but there is evidence to suggest that a significant amount were.
Much of that had already been used by patients, but a significant amount was pulled off the market.
Though much of this product was clearly destined for Vietnam, authorities believe that a significant amount was also traded within the large Czech-Vietnamese community.
The majority of my time was spent using the Twitter app Tweetbot, and a significant amount was wasted playing Zynga Poker.
More suggestions(17)
a large amount is
a substantial amount is
a tremendous amount is
a significant complaint is
a significant minority is
a similar amount is
a significant change is
a significant difficulty is
a significant proportion is
a significant reason is
a significant extent is
a significant contribution is
a significant customer is
a significant question is
a fair amount is
a significant amount does
a significant effort is
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com