The phrase "a significant alteration when" is correct and usable in written English.
It can be used to introduce a condition or situation that leads to a notable change or modification in a particular context.
Example: "There was a significant alteration when the new policy was implemented, affecting all employees' work schedules."
Alternatives: "a major change when" or "a considerable modification when".
P value is considered to be significant alteration when it is lower than 0.05.
Methylation status of the H19 and Lit1 Imprinting Control Regions in kidney, muscle and tongue of offsprings from grafted mice does not show significant alteration when compared to those of unoperated mice.
The serum hydroxyproline (Hyp) in rabbits belonging to group 1 showed no significant alteration when compared to control group.
Note that this set can be shown to be composed of approximately independent features for false positive alignments (Z-score pairwise covariances between all features did not show a significant alteration of the final Z-scores when accounting for them in all of our simulations).
In Wistar rats (A), Streptococcus was the only genus that presented a significant alteration within its abundance, while untrained rats were more enriched with Streptococcus when compared to post-exercise (p < 0.05).
A significant alteration of morphology was observed in the spinal cord tissue from SCI mice when compared with sham-operated mice (Figures 1c and 1d respectively).
Similar to HOC8, the O2 insensitive cell lines, SKOV3 and HeyA8, did not display a significant alteration in the proportion of cells in the G2 phase of the cell cycle when grown under 3% O2 or 21% O2 (Table 1).
The reasoning behind this was that such a significant alteration in social attitudes can be effective only if instituted at the earliest possible age, when the child's nature is pliant and unformed.
When the cell cycle was inhibited prior to administration of the Schedule III regimen, there was a significant alteration of the efficacy of combination treatment (Fig. 4C).
He has worked with the pitching coach, Mel Stottlemyre, apparently making a significant alteration to his delivery to keep him from telegraphing his pitches.
