Sentence examples for a shift in localization from inspiring English sources

We find both disruption of the guanyl nucleotide exchange activity of the modified Vav 3 as well as a shift in localization to the membrane upon phorbol ester treatment.

Mitochondrial subfractionation demonstrated a shift in localization of mature OSCP to the OMM in cells treated with hsp90 or proteasome inhibitors.

Further, size exclusion chromatography of J774A.1 cells treated with LT revealed a shift in localization of caspase-1 from a low-molecular weight fraction containing ASC to a high molecular weight fraction containing Nlrp1b, but not ASC [13].

Notably, pre-treatment of SCC4 cells with GS (50 µM) for 4 h, followed by ST (20 µg/ml) treatment for 6 h or nicotine (10 µM) for 4 h, showed a shift in localization of Bax and Bad and majority of these proteins were observed in the mitochondrial fraction (Figure 5B).

As colorectal cancer forms, there is a decrease in gap junction activity and Cx43 expression as well as a shift in localization of Cx43 [ 4, 5, 24].

To our knowledge, this is the first report of a shift in localization at the metaphase-anaphase transition, which may reflect separase function in sister chromatid resolution.

We have demonstrated that Tyr1022Cys induces a shift in the localization of GeaA1 at the expense of its early Golgi localization.

Yet, modification of adenoviral tropism, especially fiber gene engineering, can induce deficient intracellular trafficking of the viral particle, with a shift in subcellular localization resulting in extensive exocytosis.

Houle et al. [ 9] observed a shift in protein localization of KAI1 from the membrane in grade 1 tumors to the cytoplasm in grade 3 tumors.

For example, in cerebellar granule cells in the external granule cell layer, golli is localized in cell processes, but after their migration into the inner granule cell layer there is a shift in golli localization to the nucleus (Landry et al., 1996).

In contrast, large MDA-MB-231-RFP tumors containing necrotic regions accumulated STL-6014 approximatelyely the same rate, followed by a shift in STL-6014 localizatoon thethe central necrosis, where it reached peak concentration by 48 to 72 hours post-injection.