For instance, fetuin-A shares sequence similarity to insulin receptor tyrosine kinase [32], [33] and type II TGF-β receptor [34], and has thus been proposed as an inhibitor of insulin or TGF-βsignaling pathways.
Phylogenetic analysis provides strong evidence for ancestral centromere repeats and a shared sequence motif within it (figs. 2 and 3), suggesting that they evolved from a common ancestor.
The nested PCR method was used to amplify a shared sequence of PARV4 and its variant PARV5 and was specific for the open reading frame 1.
OrthoMCL clustering was performed against the Vibrio vulnificus reference genome CMCP6 and clusters were formed based on a shared sequence similarity of 90%, instead of the OrthoMCL default parameter of 50%.
Here, we identified transcripts of a protein that shares sequence similarities with PGRP-SB1 from several Drosophila species (Fig. 3A).
Buforin 2 (BF2) is an antimicrobial peptide that shares sequence identity with a fragment of histone subunit H2A and whose bactericidal mechanism depends on membrane translocation and DNA binding.
AS 1391, a Late gene product, shares sequence similarity with Drosophila Rab-protein 11.
CSP-2 was first identified as a caspase homolog that shares sequence similarity to both catalytic subunits of CED-3.
Q8NGU9_Hum forms a separate branch, but shares sequence similarity with AVP receptors and might bind to similar neuropeptide ligands.
LACTB is a mammalian protein comprised of a mitochondrial import sequence and a domain sharing sequence similarity to PBP-βLs (human LACTB, [Swiss-Prot: P83111]).
This approach is based on the assumption that members of a species share sequence attributes that are absent in a sister species [19].
