These data reveal a role for lysosomal membrane permeabilization in the cellular response to bacterial pathogens and demonstrate a shared requirement for cytosolic relocalization of cathepsins in pyroptosis and pyronecrosis.
BBC1 and BBC2 currently have a shared requirement to show 1,500 hours of children's programming a year.
Hence, the acquisition of insulinergic fate by endocrine organs of different evolutionary origin (Jorgensen et al., 1998; Wang et al., 2007) may reflect a shared requirement for a local source of insulin release close to the intestine.
During evolution, the shared requirement of micro- and macroorganisms for this important nutrient has shaped the pathogen-host relationship [ 14].
This shared requirement of the transmitter system between visual and olfactory learning has been described in crickets (Unoki et al., 2005, 2006; Mizunami et al., 2009).
These structure/function homologies extend to common pathologies, including shared requirements of nephrin in the maintenance of the ultrafiltration barrier, and of nephrocystins in preventing the development of tubular cysts.
Mutual unintelligibility of orthologous Foxf enhancers in spite of shared requirement for the MAPK pathway in TVC fate specification.
These artefacts have two main roles – one which enables a shared understanding of requirements and one which facilitates the development process itself.
The cycle starts with requirements analysis, during which designers should work to establish a shared understanding of the requirements, collaborate to identify technical challenges and potential technologies, and prioritize their work against developer swim lanes.
A precise, well-formed, and unambiguous definition is a requirement for a shared understanding of the term big data.
Often this activity involves numerous iterations before a shared understanding of the product requirements is achieved since various omissions, ambiguities and assumptions have to be resolved.
