Both ER isoforms share modular structures characteristic of the NR superfamily, which include six functional domains (Fig. 1) [ 9].
One possible interpretation of these findings is that the increase of local robustness and the decrease of global integration reflect a variation in modular structure of the network.
We report a modular structure of cell internalization in Caenorhabditis elegans gastrulation that reveals mechanisms of self-organization.
Based on the results, we will propose a new network inference approach utilizing the phase locking index, and examine the modular structure of the networks constructed and the biological themes shared by genes in the network modules.
The highly modular structure of chloroplast metabolism is possibly a prerequisite for a higher photosynthetic efficiency because a high modular structure can response to environmental or internal changes in a more coordinated and robust way.
Another knockdown of interest requires a slight modification of the model which underlines the modular structure of our general model.
In effect, by looking at the modular structure of the dominant patterns one gets an idea of the connectivity kernel.
All PKDs share a common modular structure, with a tandem repeat of zinc finger-like cysteine-rich motifs at their NH2 termini that display high affinity for DAG or phorbol ester, a pleckstrin homology domain (PH domain) for negative regulation of kinase activity [ 9], and a C-terminal catalytic domain containing transphosphorylation and autophosphorylation sites.
Nicolini, C. & Bifone, A. Modular structure of brain functional networks: breaking the resolution limit by Surprise.
The modular structure of the network was identified using Infomap clustering, which revealed a highly modular network (modularity coefficient=0.70), with modules corresponding to sets of strongly associated variables mixed across classes.
As expected, since this destroys the modular structure of the network, virtually no candidates were found.
