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A dot was generated using a combination of a Perl script and the "conditional formatting" function within Microsoft Excel, and highlighted by linking the horizontal position in one map and the vertical position in the other map for a shared marker between the two maps.
The pattern that emerges from these studies is one of impulsivity as a shared marker that is therefore proposed to reflect the predisposition to develop a range of addictive disorders, including gambling disorder but also conceivably other non-drug-related risky behaviors, such as risky sexual behaviors.
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With this rationale in mind, neuropsychological studies have compared groups with gambling disorder and substance use disorders against nonaddicted controls, identifying impulsivity as a key shared marker.
Ideally, all shared markers would be colinear, but in many situations discrepancies needed to be resolved.
This substantial number of shared marker loci facilitated the production of a consensus map.
Sequence data indicated that there were identical 801-bp nucleotide sequences in the shared marker RA1-PA cloned respectively from clones P and A, and the shared marker RA2-EF (which was cloned from clones E and F), were also of identical 958-bp nucleotide sequences.
Based on shared marker alignment, the 98% of the mapped SSR markers were colinear with those on the consensus map.
Exceptions to this shared marker order were found within HG04, and between HG07 and HG08.
On average, 13 shared marker loci were present on each linkage group.
A comparison of shared markers between this study and a published foxtail millet map (Jia et al. 2009) indicated that, except for one mismatch where a marker (Millet-b159) was expected on LG 6a (or LG 6b) but was actually mapped on LG 8b, the other seven markers showed consistent correspondence of LGs between switchgrass and foxtail millet.
A conflict region should include at least a pair of shared markers, the order of which in at least one set is opposite to the order in other sets.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com