The alternatively spliced exon is homologous and highly similar to the C-terminus of ZIPk, thus generating a novel DRP-1 kinase isoform which shares functional characteristics with ZIPk.
This indicates that PBEC and KC not only share structural characteristics, but may also share functional characteristics.
In addition, recent studies have revealed the importance of innate lymphoid cells that share functional characteristics with T cells [ 119].
Innate lymphoid cells are more recently discovered innate cell types that develop from an Id2-dependent common lymphoid progenitor and share functional characteristics with differentiated T cells (reviewed in ref. 50).
In addition, CRGs potentially share functional characteristics and network features in protein interaction networks (PPIN).
In summary, these results demonstrate that MtNup188 and MtNup192 share functional characteristics with NTRs and translocate across NPCs by facilitated diffusion without a requirement for other cytosolic factors.
Interestingly, while the normal CNOX isoform and tNOX share functional characteristics, CNOX appears to lack the quinone binding motif EEMTE (Chueh et al, 2002a), a fact that could explain why both enzymes differ primarily in their sensitivity to these drugs.
An important shared functional feature of this group is the resistance to osmotic pressure of up to 30 MPa, a unique characteristic when compared to normal atmospheric pressures of 0.1 MPa [ 10, 14].
Five genes were grouped into cluster 4, but they did not share any functional characteristic.
This hypothesis is corroborated by the fact that tumors of the distal bile duct and the pancreatic head also share the functional characteristics: a similar growth pattern, poor response to conventional chemotherapy, and a fairly unfavorable prognosis.
The high density of IL-1 genes in this region, which share similar functional characteristics, raises the question if an association between a haplotype in IL-1RN and prostate cancer, in fact is an association between another gene or genes in the cluster and prostate cancer.
