The phrase "a shared function in" is correct and usable in written English.
It can be used to describe a common role or purpose that multiple entities or components have within a particular context or system.
Example: "The software components have a shared function in ensuring data integrity across the platform."
Alternatives: "a common role in" or "a mutual function in".
A common statistical method for testing whether a particular group of genes with a shared function occurs more frequently in a cluster than would be expected based on random sampling of the microarray data set is the application of the hypergeometric distribution [25].
To this end, we took the same set of gene pairs which were found to have a highly specific shared function in the previous study by Mani et al. [14] (see Methods for their definition).
We observed some slight evidence of shared function in a few specific cases largely driven by the few genes that were in common to more than one diet (Table S9 and File S5), but observed no generally compelling pattern.
The proteins were assembled within clades of proteins that are aligned along their full length (no missing functional domains), and that allow high confidence of shared function in each species.
Despite their independent functions, studies have shown that the activities of these enzymes are co-regulated, likely due to their shared function in maintaining cellular pools of NADPH for use in a number of downstream processes, such as lipogenesis, antioxidation, and immune response (Geer et al. 1976; Wilton et al. 1982; Bentley et al. 1983; Merritt et al. 2005, 2009).
The shared function in dsx regulation across the different insect orders thus suggests that the role of Tra2 proteins in regulating female dsx splicing is the ancestral state in holometabolous insects.
In addition to contributing to our knowledge of molecular evolution, the presence of duplicated genes with shared function in the zebrafish genome provides the novel opportunity for fine-tuned analyses of gene regulation.
Thus, we have identified two modulators of the Wnt pathway that have shared functions in cell division, which hints at a possible link between cytokinesis and Wnt activity during tumorigenesis.
In this work, we present a sensitive and accurate HMM-based pipeline for predicting proteins with shared functions, in this particular study with putative virulence or effector functions, based on a comparative analysis and a subsequent protein clustering step.
