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A shared drawback of the cameleons, CatchER and GAP1 is that they require use of blue light for excitation, which leads to relatively high levels of autofluorescence and phototoxicity, and prohibits simultaneous imaging with green fluorescent indicators.
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Therefore, it shares drawbacks of using administrative datasets in evaluating quality such as inability to specify clinical definitions for risk factors (e.g., forced reliance on ICD-9 codes), and limited ability to distinguish between complications of care and pre-existing conditions.
The women have never played in a Final Four, never earned a No. 1 seed, and went 30 years before winning a Southeastern Conference regular-season title this season — a drawback of sharing a conference with Tennessee.
But side by side with the presumed benefits of policy, many analysts share the opinion that a major drawback of health policies is their failure to make room for issues of human resources.
Except the methods that are based on the task dynamic (TD) model, most of them, however, share the common drawback of the mapping paradigm, i.e., the lack of the inclusion of speech production mechanism in the modeling process, in particular, the dynamic movement of speech gestures [1, 2] that results in smooth spectral transitions observed in the natural acoustic data.
A major drawback of these schemes is the high communication overhead when path keys are sought to establish shared keys between neighboring sensors.
Millipede still suffers a big drawback of mechanical systems.
Weight is a major drawback of the ViewPad.
A major drawback of reverse mortgages is high closing costs.
A possible drawback of agentialism is its limited application.
This is a major drawback of all studies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com