Most substrates that enter the central metabolism at the starting point of the citric acid cycle, i.e. as acetate or oxaloacetate, caused a severe repression of pigment production, which resulted in unpigmented cells after several transfers in the same medium.
One striking feature of this initial phase is a severe repression of nuclear-encoded genes involved in all steps of the Chl a metabolism, suggesting a light dependent and synchronised regulation of the transcription of these genes (Figure 1).
However, the genes included in cluster 7 exhibit a more severe repression in the P5 condition than in the P15 condition which may reflect a differential transcriptional response as a function of oxidant concentration.
After a period of severe repression and sluggish growth after the crackdown, China rebounded.
How can you not love her?" Despite a period of severe repression in the 1990s, Christianity has blossomed in China.
Late last week, the Swedish foreign minister, Carl Bildt, forecast a period of severe repression, with hard-liners in command in Cairo, but said the Europeans should keep talking to all sides so as to be ready, if the opportunity arose, to play a role in achieving a solution.
Or that in the eleventh and fourteenth centuries, we faced onerous taxes, the destruction of several synagogues, and severe repression?
Mr. Smith's resistance to black rule led to a unilateral declaration of independence from Britain in 1965 and, later, severe repression and a seven-year guerrilla war, costing about 30,000 lives, most of them black fighters and civilians.
Those who stayed in their homes face severe repression in a police state which maintains an armed force over 100,000 strong for a population of just 500,000.
Because in an age where there's so much active misinformation, and it's packaged very well, and it looks the same when you see it on a Facebook page or you turn on your television, where some overzealousness on the part of a U.S. official is equated with constant and severe repression elsewhere, if everything seems to be the same and no distinctions are made, then we won't know what to protect.
ISIS, for example, grew as a result of the U.S.-backed Iraqi government's severe repression of Sunnis; most of its members don't even seem to know much about religion.
