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The lack of these features will become a severe problem since scalable and modular solutions cannot be provided when integrating new wired/wireless devices into existing automation systems.
Contaminating human DNA constitutes a severe problem since it may be indistinguishable from the endogenic DNA (especially if the donors are ethnically related to the subjects), and exogenic DNA may, after relatively few years, accumulate damage patterns that are similar to those of the endogenic DNA [39].
In most high-throughput assays, this is a severe problem since there is no means for correcting for differences in enzyme concentration.
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The recruitment of k-mers from one contig to an unrelated contig (as shown in Fig. 6) presents a severe problem to NGS assemblers, since the position of k-mers cannot be ascertained prior to assembly.
Nevertheless, overcrowding remains a severe problem.
The proposal would address a severe problem.
But there was a severe problem.
Food waste is a severe problem in China.
There's also a severe problem of timing.
"It is really a severe problem in our society today".
"Unemployment is a severe problem," said Zhong Dajun, who runs an economic research center in Beijing.
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