Sentence examples for a severe limitation from inspiring English sources

The problem may be a severe limitation to numerical modeling.

At St. Martin's, his lack of drawing skill was a severe limitation.

It illustrates a severe limitation to our learning from observations or experience and the fragility of our knowledge.

Scarcity of water is a severe limitation in citrus tree productivity.

That ruling posed a severe limitation because in the months after the invasion, American officials used seized Iraqi cash and Iraqi oil revenues to pay many contractors.

Other materials, for example, paramagnetic salts, are commonly used for the same purpose but none of them is metallic, a severe limitation for low-temperature applications.

A severe limitation imposed by many continuum damage mechanics models is the assumption of initial isotropy in many anisotropic damage models.

The unusual conditions for crystallisation used gave the polymer molecules a severe limitation to rearrange from the initial random coil state.

But the tests have a severe limitation: They may fail more than half the time to detect swine flu infections, according to newly published studies and to experts in medical testing.

However, the short half-life of the Fab, due to its low molecular weight, is a severe limitation for the deployment in therapy.

This is a severe limitation as many proteins, including cytokines, growth factors, enzymes, and receptors have molecular weights exceeding 25 kDa.