Sentence examples for a severe language from inspiring English sources
For example, a patient could be "nonverbal" for a variety of reasons, including a severe language disability such as aphasia or congenital deafness, conditions which require quite different accommodations.
Independent intragenic deletions in both Xq21.3 and Yp11 involving PCDH11X and PCDH11Y have been identified in a single case of a male child with a severe language delay (Speevak and Farrell 2011).
Heterozygous mutations of the human FOXP2 gene are implicated in a severe speech and language disorder.
FOXP1 is related to FOXP2, which is involved in a severe speech and language disorder (Lai et al, 2001).
The three patients had moderate intellectual disability (IQ of <50), gross motor delay and a severe speech and language defect, characterised by a delay in the onset of speech, dysgrammatism and very poor speech articulation.
Among cases described to date, Orellana et al. (2008) noted striking variability in phenotype, including good social skills in several individuals, but severe language delay as a highly consistent symptom.
82– 85 Independent intragenic deletions in both Xq21.3 and Yp11.2 involving PCDH11X and PCDH11Y have been reported in a case of a male child with severe language delay.
Interestingly, each individual with either a deletion of SHANK3 or a truncated protein had severe language problems, whereas the individual with 22qter partial trisomy had precocious language development and fluent speech, but social communication difficulties.
A recent study of 38,954 children in the Norwegian Mother and Child Cohort Study found that peri-conceptional maternal intake of FA supplements was associated with a lower risk of severe language delay at age 3 years [ 98].
Duplications of the WBS critical region in 7q11.23 have also been described in several patients with ASD, severe language delay and mental retardation [ 55].
The resulting subgroups included one with severe language impairment, another with mild severity across all items, a third of intermediate severity, and a fourth of moderate severity with a higher frequency of savant skills.
