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When lasers were first invented, laser speckle was considered to be a severe drawback in using lasers to illuminate objects, particularly in holographic imaging because of the grainy image produced.
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The occurrence of significant degradation by β-scission reaction is a severe drawback affecting the classical procedure of polypropylene (PP) functionalization in the melt with maleic anhydride (MAH) or derivatives and free radical initiators.
On the other hand, the failure of the compactness theorem to generalize to L ω1,ω) in any useful fashion is a severe drawback as far as applications are concerned.
"This is a severe drawback," says Andy Hall, a pharmacogenomics researcher and director of the Northern Institute for Cancer Research at the University of Newcastle-upon-Tyne in England.
However, there is a severe drawback that pixels locating at the lower and central parts of an image are likely to be assigned with nearer depths, resulting in a smoothly tilted depth pattern for most input images.
We assumed that wetland area loss would be a severe drawback for them along their migration routes.
The Evil Dead fails even to horrify – always a serious drawback in a horror movie.
However, they suffer from severe drawbacks in terms of their membrane penetration mechanisms that mainly include endocytosis and pore formation.
However, it also means the actual alleles fixed under the artificial selection regime may have severe drawbacks in natural conditions.
However, this leads to an even more severe drawback, unmet demand.
Both approaches have severe drawbacks, as in the first approach potentially useful information is discarded while in the latter approach similarities across cell stages are not considered.
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CEO of Professional Science Editing for Scientists @ prosciediting.com