The phrase "a severe disruption" is correct and usable in written English.
It can be used to describe a significant interruption or disturbance in a process, system, or situation.
Example: "The storm caused a severe disruption in public transportation, leaving many commuters stranded."
Alternatives: "a major interruption" or "a significant disturbance."
The Saudis are the only ones with enough spare oil-field capacity to call on if there is a severe disruption elsewhere.
But Mr. McClellan rejected the notion, saying it "would have a negligible impact" on prices and that it was "important that we have the necessary resources in the event of a severe disruption of supply".
A severe disruption in business is particularly damaging to a personal-injury firm, which depends on referrals from other lawyers and advertising, rather than on the long-term clients that fuel a white-shoe downtown firm.
WASHINGTON (AP) — The student lender Sallie Mae said on Wednesday that it lost $104 million in the first quarter, falling short of Wall Street's expectations amid a severe disruption in the student lending industry.
Although America is steadily reducing our own dependence on imported oil, the world still depends upon the region's energy supply, and a severe disruption could destabilize the entire global economy.
Agriculture minister Brendan Smith explained this week that "it has been a matter of great concern to Ireland, in recent years, that there has been a severe disruption to trade of animal feed, caused by the delays in the authorisation, by the EU, of GM varieties which have already been approved in the exporting countries".
Treatment of starved Fabry disease fibroblasts and lymphocytes with lysosomal protease inhibitors reveals a block in autophagic flux, demonstrating a more severe disruption of degradation through macroautophagy than that observed in other sphingolipidoses.
The loss or reduction of the D2013.9 gene product by RNAi knockdown results in a very severe disruption of the myofilament lattice.
Because of its critical positioning, the mutation of R179 might cause a more severe disruption of actin polymerization than other mutations, which may explain the more severe and generalized phenotype reported for R179 mutations [ 12].
The alterations were dependent on the time of cell administration, significant morphological changes took place 15 weeks after cell administration, and a more severe disruption of the alveolar walls occurred after 30 and 60 weeks.
The interaction is important because it indicates that the removal of the landmark from the platform, thus forcing subjects to rely solely on the boundary cues to find the platform, resulted in a more severe disruption in performance for the hippocampal than the sham group.
