The phrase "a severe disorder of" is correct and usable in written English.
It can be used in medical or psychological contexts to describe a serious condition affecting a particular part of the body or mind.
Example: "The patient was diagnosed with a severe disorder of the nervous system that required immediate treatment."
Alternatives: "a serious condition of" or "a critical illness of".
Congenital muscular dystrophy type Ullrich (UCMD) is a severe disorder of early childhood onset for which currently there is no effective treatment.
X-linked hypophosphatemic rickets (XLHR) is a severe disorder of phosphate homeostasis and skeletal mineralization caused by mutations of PHEX, encoding a bone-specific endopeptidase.
Coma is a severe disorder of consciousness that is characterized by a deficiency of behavioral responsiveness as well as disturbances in sleep-wake cycles that include extended periods of eye closure and muscle inactivity [1].
Complete absence of ACE in humans leads to renal tubular dysgenesis (RTD), a severe disorder of renal tubule development characterized by persistent fetal anuria and perinatal death.
Two mutations in ACE have been described which were linked to premature fetal death due to autosomal recessive renal tubular dysgenesis -RTD [24] [25], a severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (Potter phenotype).
Preeclampsia (PE) is a severe disorder of human pregnancies affecting up to 10%% of primiparous women in industrialized countries.
A total score above 20 indicates high levels of functional impairment associated with a severe disorder; scores of 10 - 20 indicate significant impairment associated with mild to moderate level disorders; and scores below 10 are typical of a non-clinical population.
Congenital adrenal hyperplasia is a severe disorder with an impairment of adrenal and gonadal steroid synthesis.
Its mutational inactivation in humans causes autosomal recessive cutis laxa type 1C (ARCL1C), which is a severe disorder caused by defects of the elastic fiber network.
On the other hand, premature discontinuation of antipsychotic medication has the potential risk of early relapse of a severe disorder.
CD is a severe disorder that affects the development of the skeleton and reproductive system.
