Sentence examples for a severe diminution from inspiring English sources

Thus, a severe diminution of TNF-α can delay tumor colonization by S. Typhimurium but does not abolish it.

Beside him stood his Chancellor of the Exchequer, George Osborne, and a formidable mustering of allies, including a throng of economic bodies — the Institute for Fiscal Studies, for example, which foretold a severe diminution of the U.K. economy in the event of a win for the Leavers.

Taken together, all of these threaten a severe diminution of the status of the University of California, long considered the nation's - perhaps the world's - premier research university.

Knockdown of endogenous NKX2.2 results in a severe diminution of oncogenic transformation (Figure 1B; ref. 8).

Deletion of Ada1, an adaptor protein necessary for the structural integrity of SAGA, led to a more severe diminution of gene expression of ADH2 and FBP1, as well as reductions in expression of ADY2 and JEN1 suggesting that SAGA is important for appropriate gene expression both in its capacity as a HAT as well as another, non-HAT function.

In other words, the potential odorant recognition of humans may have suffered only a minor damage by the severe diminution of their OR repertoire.

Thus, cardiac ilk KD with hand- Gal4 is likely to cause more severe diminution of ilk function than the expected 50% reduction in function of ilk heterozygous mutants or with GMH5-mediated KD (see Fig. S3).

"That would be a serious diminution to our lifestyle," he said.

However, a systematic exploration of respiratory function in January 2000 showed a severe hypoxia and confirmed the diminution of carbon monoxide capacity found 5 years earlier.

A severe economic slowdown.

A severe depression followed.