The phrase "a severe delay" is correct and usable in written English.
It can be used to describe a significant or serious postponement in various contexts, such as travel, project timelines, or event schedules.
Example: "Due to unforeseen circumstances, there was a severe delay in the delivery of the project."
Alternatives: "a significant delay" or "a major delay".
Absence of the post-transcriptional modification of the wobble anticodon position of the cytoplasmic tRNALys has been shown to cause ribosome pausing on lysine codons, inducing a severe delay in the rate of translation elongation10,11,12.
In response, the petrol station says there is a severe delay in getting due money back from local government authorities.
Compared to controls, the mice experienced a severe delay in the migration of neurons in their brains, leading to abnormal brain development.
Therefore, we believe that lack of linear progression in intron removal is not caused by a severe delay promoted by the GAG.
However, by forcing the de novo functioning of the OXPHOS system, a severe delay in the biogenesis of the respiratory chain complexes was observed in the mutants, which demonstrated a direct functional effect of the mitochondrial genetic background.
The double mutant displayed a severe delay in flowering, together with additional pleiotropic phenotypes.
Compared with partial root-zone cooling, full root-zone cooling may result in a more severe delay of hormone production that favours flower development.
Rbp4−/− mice fed a vitamin A-deficient diet during NC development had striking ENCDC migration delays in the colon compared with Rbp4−/− mice fed a diet containing vitamin A. Additionally, Rbp4−/−, Ret+/− mice had a much more severe delay in ENCDC colonization of the bowel when deprived of dietary vitamin A and even manifested a significant developmental delay when fed a vitamin A-sufficient diet.
At the cellular level, all COG mutations display a significant mild to severe delay in BFA-induced redistribution of Golgi enzymes (as evidenced by mannosidase II) or Golgi matrix proteins (such as GM130) to the ER, ER exit sites or perinuclear vesicular structures (32, 39, 40).
Five out of 282 long-term survivors had a mild developmental delay and two infants had a severe developmental delay.
As a result he had many physical problems early on and currently struggles with a severe speech delay".
