Mutant age3Δ cells have a severe defect in filament formation under several different hyphal growth conditions.
On Monday, doctors removed Beatriz's fetus — which had a severe defect that prevented the brain from developing — through an incision in her abdomen.
These observations suggest that the acquisition of motor skill may remain relatively unaffected by lesions that give rise to a severe defect of general memory.
For example, the knockout mutants of GAMYB in rice showed a severe defect in spikelet development, particularly in anther and pollen development (Kaneko et al. 2004).
Limbal stem cell deficiency (LSCD) is a severe defect of the limbal stem cells leading to vision loss due to conjunctival epithelial invasion and neovascularization.
Consistent with the roles for these cytokines in Treg differentiation in the thymus, in mice with a T cell-specific deficiency in STAT5 expression a severe defect in Treg development was observed (Burchill et al., 2007).
In contrast, the pri2(C417A, C474A, C474A) mutant permanently arrested with a G1 DNA content after being released from G1 at 37°C, indicative of a severe defect in initiation of DNA replication.
It is an attracting goal, but the fact is a little bit depressing, for there is a severe defect, called information isolated island, in the information system of the power supply companies.
Decreased transcription in neurons was coupled with a significant reduction in nascent protein synthesis and lack of MECP2 was manifested as a severe defect in the activity of the AKT/mTOR pathway.
Accordingly, TGFβ1-deficient mice display a severe defect in LC, but not in DC, development [21].
Studies have determined that MyD88-deficient mice display a severe defect in host defense against B. burgdorferi infection [48], [49].
