The phrase "a severe bottleneck" is correct and usable in written English.
It can be used to describe a significant obstacle or limitation that hinders progress or efficiency in a process or system.
Example: "The outdated software created a severe bottleneck in our production line, delaying deliveries."
Alternatives: "a major hindrance" or "a critical obstruction".
A severe bottleneck occurred in the Middle Ages, reducing the population to under 350 individuals.
We can do a couple of things at the same time if they are routine, but once they demand more cognitive process, the brain has "a severe bottleneck," he said.
We demonstrate that the persistence of mitochondria may be explained by recent data that point to a severe "bottleneck" in the number of mitochondria passing through the germline in humans and other mammals.
Fossil evidence for modern humans goes back at least 500,000 years so it seems that humanity went through a severe bottleneck when this Eve was alive - it remains a mystery why of all the females who inhabited the globe at that time, she was the only one to leave modern descendants.
A severe bottleneck exists during HIV-1 mucosal transmission.
This has led to medical image interpretation becoming a severe bottleneck in healthcare today," he tells me.
For Hawaii (K2), the posterior distribution displays values lower than 1 and shows a peak at 0.59 indicating a more severe bottleneck than in Australia (Fig. 4E).
The coalescent likelihood framework assumed two classes of genes, genes affected by the domestication bottleneck alone and a second group of genes that went through a more severe bottleneck representing the effects of both the domestication bottleneck and selection.
Patterns of diversity suggest differences in current Ne between D. miranda and D. pseudoobscura; however, the dadi estimator suggests a recent severe bottleneck for D. miranda (see Results) but a more similar long-term Ne for most of their history.
Recently, a detailed microsatellite analysis has suggested non-independent domestication of indica and japonica, although this research found a more severe bottleneck to the establishment of japonica than to that of indica [11].
Ancient population size of S. squarrosum is considerably larger than that of S. fimbriatum indicating a more severe bottleneck in the latter.
