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The phrase 'a setback to' is correct and usable in written English.
You can use this phrase to describe something that hinders a process or development. For example: The introduction of a new tax was a major setback to the company's growth plans.
Exact(60)
"It looks to be quite a setback to the industry".
The Los Angeles strike dealt a setback to that agenda.
The passage of Proposition 23 will be a setback to efforts to address climate change globally.
The surge was a setback to hopes that layoffs were declining.
It is also a setback to his plans to reform the army.
His misbehavior, however, is a setback to the hierarchy's efforts to repair the church's reputation.
A humiliation for BP in Russia would be a setback to this charm offensive.
It is also a setback to the country's efforts to reduce pollution.
How much of a setback to growth do these twin crises represent?
In the minds of many shark researchers, the movie was a setback to white-shark science.
The extension is seen as a setback to progress in African governance by the international community.
More suggestions(23)
a setback to him
a vital setback to
a setback to understanding
a setback to those
both a setback to
a defeat to
a blow to
a impediment to
a rollback to
a kickback to
a backlash to
a disappointment to
a reversal to
a relapse to
a retreat to
a regression to
a drawback to
a downturn to
a backhand to
a failure to
a recession to
a throwback to
a backsliding to
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com