This approach is useful when dealing with especially small datasets, where splitting the data would result in a training set of insufficient size.
Due to the relative scarcity of high severity ratings on certain Revised SCOPA-DC items, CV scores could not be evaluated for a number of patients, yielding a set of values with insufficient variation to effectively test the validity of this measure.
We can infer that when a profile HMM captures insufficient signal from a set of sequences, the sensitivity of the HMM can be improved by including mutated sequences in the training set.
Equally, utilising a set of just 96 SASI fragments is likely to be insufficient for a lab handling thousands of samples each month.
The GEP has developed a set of annotation guidelines (Annotation Instruction Sheet) to standardize the treatment of annotations that are ambiguous because of insufficient evidence.
Heavily invested research has been initiated based on etiological models of unrealistic simplicity and conducted under poor experimental designs, on data sets of insufficient size, leading to an overestimation of the effect sizes of genetic variants and the quantity and quality of linkage disequilibrium (LD).
Necrosis occurs in solid tumors in the setting of insufficient blood supply during the natural history of the disease or as a response to therapy.
Excessive glucagon signaling, due to elevated glucagon levels and lack of glucagon suppression, in the setting of insufficient hepatic insulin action contribute to disproportionate hepatic glucose production (Lin and Accili Cell Metab., 2011, 14 9-19).
For very complicated molecules, such as many natural products that occur in living organisms, even a complete set of spectra is insufficient to allow an unambiguous structural assignment.
This should not be surprising; half the state's evaluations are based on those scores, a system that numerous scholars have called inappropriate due to an "Imprecise" set of estimates and "insufficient" research base.
