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The phrase "a serious uncertainty" is correct and usable in written English.
It can be used when discussing a significant doubt or lack of clarity regarding a situation or outcome.
Example: "The recent data has led to a serious uncertainty about the project's future success."
Alternatives: "a significant doubt" or "a major ambiguity."
Exact(1)
For Milton, this is a serious uncertainty, not just a way of sounding modest.
Similar(59)
A serious doubt now.
HIV creates a situation of serious uncertainty for public health interventions based on pre-HIV era models [ 10, 11, 13].
"Since the eurozone is still in the grips of some serious uncertainty," she said, "the Swiss franc is once again a safe-haven currency".
The fourth annual draft, held in Kansas City, Mo., took place amid serious uncertainty about the future of the league.
But all of this presents some serious uncertainty.
The novel control strategy combining sign function with delicate adaptive technique can handle serious uncertainty and nonlinear growth rate.
But, many organizations and supporters of the campaign on unlocking have argued that this legislation is insufficient as it would provide serious uncertainty to the market – in two years unlocking would likely be illegal all over again.
For Canada's 29 licensed pot producers that operate under the MMPR, this decision creates serious uncertainty.
Nevertheless, having AIG's emblem on the wall doesn't exactly help Donohue make the case (as he did on Tuesday) that businesses face serious uncertainty -- and possible calamity -- if proposed reforms of the financial sector are implemented.
Unfortunately, for the reasons outlined above there is now serious uncertainty about appropriate usage of the term 'Data Safe Haven'.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com