The phrase "a serious setback after" is correct and usable in written English.
It can be used to describe a significant obstacle or difficulty that occurs following a particular event or situation.
Example: "The team faced a serious setback after the unexpected loss of their key player."
Alternatives: "a major obstacle following" or "a significant hindrance after".
The murder case against Shrien Dewani has suffered a serious setback after the trial judge stopped a male prostitute from giving evidence against him.
Women's rights in Iran have also suffered from a serious setback after the authorities last year reversed the country's progressive laws on family planning by outlawing voluntary sterilisation and restricting access to contraceptives.
Neither party will get anything like the vote (28% for the SNP and 29% for Plaid) that it got in the 1999 assembly elections.So, among the claims that Mr Blair will be anxious to make on June 8th will be that the nationalists have suffered a serious setback after the upward surge in their vote in recent years (see chart).
David Cameron suffered a serious setback in Scotland after seeing a wave of tactical voting lead to increased majorities for Labour and Scottish nationalist candidates in a series of key Tory target seats.
MANILA — Negotiations between the Philippine government and Islamic separatists suffered a serious setback over the weekend after the insurgents accused the government of unilaterally changing the essence of the draft of an agreement on ancestral homelands.
After a serious setback in its fight for the Lebanese town of Bint Jbeil, Israel hints that its military objective may be downgraded from destroying to weakening Hizbullah.
That he is still around and running in major races so long after such a serious setback is difficult to believe.
Marking a serious setback for the French, the treaty was signed after Edward the Black Prince defeated and captured John II of France at the Battle of Poitiers (1356).
Everton have been dealt a serious setback on the eve of the new Premier League season after Ross Barkley suffered a training ground injury that could sideline the England international for up to two months.
Audry and her children had worried about the toll the birthday party might take on her health, but it wasn't until about a month after her actual birthday that she suffered a serious setback.
