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The phrase "a serious problem is" is correct and usable in written English.
You can use it when introducing a discussion about a significant issue or concern that needs to be addressed.
Example: "A serious problem is emerging in our community regarding access to clean water."
Alternatives: "a significant issue is" or "a major concern is".
Idiom
Problem is thirty.
If a problem is 30, the problem is the person who sits 30 cm from the computer screen.
Exact(14)
However, a serious problem is that the European Central Bank (ECB) seems to be reaching the end of the rope.
A serious problem is how to prevent a collapse of Greek banks if the country is declared to be in default.
And a serious problem is emerging: some are rebelling or asserting independence by skipping or stopping medication, which can make H.I.V. spiral out of control and become impervious to previously effective therapies.
The New York City Education Department, acknowledging that obesity is a serious problem, is reducing the fat content in meals it serves and is banning soda and sugary snacks from vending machines.
"All it takes to have a serious problem is for a squirrel or a bird to build a nest in the chimney," said Robert Bellini, an owner of Varsity Plumbing, a plumbing and heating contractor in Flushing, Queens.
But he added: "Where it seems we still have a serious problem is in the transition of young players – and particularly young English players – out of academies into first-team football".
Similar(44)
It was then, almost exactly 20 years ago, that the first hint of a serious problem was detected.
A serious problem was the incompatibility of the dietary recommendations with daily life resulting in a reluctance to adjust the whole diet to the needs of diabetes care.
This framing of overdiagnosis as a serious problem was grounded in a strong commitment to avoiding harm in any public health program.
A more serious problem is that the transmitter died after a couple of weeks.
A more serious problem is the moral seesawing of Costa and Sebastian.
More suggestions(3)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com