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Drug abuse is a serious problem associated with different pathological outcomes including modulating the immune system.
Material loss due to erosion wear is a serious problem associated with flow of solid-liquid mixtures.
Compromised stability of pharmaceutical formulations loaded with volatiles is a serious problem associated with devices designed to deliver volatile compounds.
PML is considered a serious problem associated with NA therapy.
Fouling of chromatographic resin over operational lifetimes can be a serious problem associated with industrial separations.
Infections with Staphylococcus epidermidis bacteria pose a serious problem associated with the use of biomaterials in modern medicine [ 1- 5].
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ClinicalTrials.gov NCT 00122226 Lipodystrophy is a common and serious problem associated with HIV infection and its treatment [1].
However, the most serious problem associated with the iliac free bone graft is a higher bone resorption rate during the early healing phase [ 8, 23].
However, the most serious problem associated with Microcystis blooms is the production of hepatotoxic cyanotoxins called microcystins.
The other, more serious, problem associated with the method is its unreliability.
However, the most serious problem associated with TBF, especially in sheep, is the following immunosuppresion, which may predispose to secondary infections [ 16].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com