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The phrase "a serious pitfall of" is correct and usable in written English.
It can be used when discussing a significant drawback or risk associated with a particular situation, concept, or action.
Example: "One serious pitfall of relying solely on technology is the potential loss of critical thinking skills."
Alternatives: "a major drawback of" or "a significant risk of".
Exact(1)
These observations helped us to identify a serious pitfall of dose-response strategy: as long as we do not have realistic prior information on the limits for which we expect the estimated values of the model parameters to be applicable, we face the risk of invalidating a true model structure by over-challenging the model.
Similar(59)
Furthermore, the lack of refined integration methods has been a serious pitfall for the possibilities for industrialization and the following commercialization of products deriving from the area.
This helps him avoid a serious pitfall, an overabundance of liquid in the pan, resulting in mushy apples and a soggy crust.
Most said failing to research the target company was a serious pitfall, too.
In a preface to "The Griffin and the Minor Canon," Sendak describes his basic aim as an illustrator: "I wanted at all costs to avoid the serious pitfall of illustrating with pictures what the author had already . . .
To be sure, the BP accident is an environmental threat that speaks to the deadly serious pitfalls of off-shore drilling.
However, other people have experienced the serious pitfalls of online dating -- "catfishing" and predators.
Still, Edmunds argues that the model points out a potentially serious pitfall for countries outside of the United States considering varicella vaccination.
In the meantime, the review is a good idea, but its serious pitfalls are reminders of the rising costs of our national failure to fix a broken immigration system.
I can understand the motivation but I think there are a lot of serious pitfalls along the way here for us to consider".
For the purposes of drug design, the temptation to screen for potential target genes by applying evolutionary analyses to whole coding sequences represents a serious potential pitfall.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com