Sentence examples for a serious issue during from inspiring English sources

But this is hardly the first time Medicare's been a serious issue during a Presidential election, or during a Presidential debate.

Clemens beat the Red Sox with six strong innings Wednesday, but his elbow became a serious issue during and after that game.

The consequences of immunogenicity, in particular the induction of antidrug antibodies (ADA), have the potential to become a serious issue during drug development, due to their impact on drug pharmacokinetics (PK), efficacy, and/or safety.

The onset of type 1 diabetes is most frequently in childhood and in view of the need for a life-long therapy, compliance to therapy is a serious issue, especially during puberty.

The brain deformation that occurs during neurosurgery is a serious issue impacting the patient "safety" as well as the invasiveness of the brain surgery.

What makes this a serious issue is that Twitter has partnered with NBC during the Olympics.

Neurodegeneration restricts neuron numbers during development but can become a serious issue in disease conditions such as temporal lobe epilepsy (TLE).

Overcrowding is a serious issue.

That is a serious issue".

"It's a serious issue.

That was a serious issue.