The phrase "a serious issue at" is correct and usable in written English.
It can be used when discussing a significant problem or concern related to a specific location, organization, or situation.
Example: "There is a serious issue at the local hospital regarding patient care standards."
Alternatives: "a critical problem in" or "a significant concern at".
Such hyperbolic claims aside, there is a serious issue at the heart of what worries critics.
Whatever the mechanics of the Good Booking initiative, there's a serious issue at stake.
The contact resistance of metal or metal silicides to the raised source drain material is a serious issue at sub-micron dimensions and must be minimised.
For the first time, vote-rigging may become a serious issue at a general election - perhaps in just three months' time.
This is a serious issue at a time when their financial performance is already lacklustre and investor pressure to break up banks growing.Worse still, other banks may fail the next round's qualitative tests.
Many only discover that there is a serious issue at the end of a tenancy, and in the time it takes to fix the problem, they lose out on rental income.
Seasonal selection bias may not be a serious issue as patients who came at different seasons of the year were recruited to the study.
Milner's decision creates a serious issue for City at a time when they are already struggling to meet the stipulations set by the Premier League and Uefa about meeting the homegrown player rule.
— ROBERT MACKEY From New Orleans, my colleagues John Schwartz and Campbell Robertson are reporting that early on Wednesday, the Army Corps of Engineers was watching a potentially serious issue at the 17th Street canal, a drainage canal into Lake Pontchartrain that reaches deep into the city and which breached catastrophically after Hurricane Katrina in 2005.
On a scale of 1 to 10, where one means anti-Semitism is not a problem at all and 10 means it is a serious issue, participants rated it at 4.66.
A friend of Life in the Boomer Lane brought up a very serious issue at their breakfast out, the other day.
