A meta-analysis, such as that conducted by Bongartz and coworkers [ 1], has the ability to overcome some of these issues and has raised the concern of a potentially serious increased risk for malignancy.
The magnitude of this decreased functional capacity suggests serious increased risk of death for participants with diabetes and COPD.
The long-term sickness absence of an individual employee is generally a symptom of an increased risk of serious health impairments [ 7].
31 The overall pooled OR of serious infections did not show a significantly increased risk of serious infection.
An example of this could be a gene mutation associated with an increased risk of a serious health problem, such as cancer.
We found a significantly increased risk of serious infection in patients who had already developed a serious infection earlier in the observation period.
IAT is associated with a number of serious consequences, including an increased risk of hospital mortality.
Using a large set of studies we found that IAT is associated with a number of serious consequences,including an increased risk of hospital mortality.
Although a slightly increased risk of serious infections has been noted in adult trials, there was no difference in serious events between abatacept-treated and placebo-treated groups in this pediatric study [ 27].
This has resulted in the US Food and Drug Adminiatration advising manufacturers that a boxed warning of an increased risk of serious cardiovascular adverse events should accompany all NSAIDs, including those available over the counter [ 31].
