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But China's unyielding support of Kim Jong-un has a serious downside, they added, because it may lead to a result nearly as unpalatable: efforts by the United States and its regional allies Japan and South Korea to contain China.
In the UK, unlike the US, there is no strong culture of university-funded financial aid programmes, which is a serious downside when comparing British universities against their counterparts around the world.
Unfortunately, it turns out that the sweet silence of 21st-century technology has a serious downside: pedestrians and bicyclists are less likely to hear hybrids and electric cars coming their way and are more likely to be clipped or run over.
Yet there is a serious downside to this approach.
But new research indicates that brawniness can have a serious downside.
Most cancer treatments come with a serious downside: They also harm normal cells.
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And it would be hard to get the Food and Drug Administration to approve a drug with any serious downside for so mild a disease.
Clarke said last month that such a development would be "a very serious downside" to the policy.
Re "Did You Get the Check I Sent?" (editorial, Aug. 6), about the explosive growth of spam e-mail on the Internet: There's a more serious downside looming that the Net marketeers and junk e-mailers have not yet considered.
Speaking about the expansion of prison work from 10,000 to 20,000 prisoners over the next decade, Clarke told the BBC last month: "It would be a very serious downside if we started replacing job opportunities for law-abiding people, and we've been conscious of that all the way through.
Concomitant improvements in communications technology, process and protocol in primary and community care are urgently required to offset a potentially serious downside to patient safety.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com