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The phrase "a serious affinity for" is correct and usable in written English.
You can use it to express a strong liking or attraction towards something.
Example: "She has a serious affinity for classical music, often attending concerts and recitals."
Alternatives: "a deep fondness for" or "a strong liking for".
Exact(1)
Fernley Phillips, screenwriter of the film "The Number 23," feels a serious affinity for that numeral.
Similar(57)
The "experiment" in the title is a license to go beyond jazz-trio territory, and possibly indulge serious affinities for hip-hop, house and soul.
But Mr. Lugo's court-appointed lawyer, James Montgomery, said the allegations revealed a problem more serious than a mere affinity for masterpieces.
Although TF binds with low affinity to the ribosome [ 28], overexpression of TF might become a serious problem for protein synthesis in the expression host.
A serious event for a serious man.
A serious time for German politicians.
This was a serious problem for me.
This is a serious job for serious people.
A: Prometheus is a Greek titan who had an affinity for human beings.
Harris has a special affinity for animals.
France, in particular, has a great affinity for his work.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com