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The phrase "a series of key differences" is correct and usable in written English.
It can be used when discussing multiple important distinctions between two or more subjects.
Example: "In this report, we will explore a series of key differences between renewable and non-renewable energy sources."
Alternatives: "a number of significant differences" or "a set of important distinctions".
Exact(3)
There are a series of key differences between the industry's royal charter plan and that agreed by politicians and campaigners.
But the newspaper industry rejected the idea of "state-sponsored regulation", putting forward a plan with a series of key differences.
There are a series of key differences between the industry's plan for press regulation and that agreed by politicians and campaigners.
Similar(57)
Here, we use mitonuclear introgression lines to assess differences in a series of key life-history traits (egg-to-adult developmental time, viability, offspring sex-ratio, adult longevity and resistance to desiccation) in Drosophila subobscura fruit flies carrying one of three different sympatric mtDNA haplotypes.
If life is a series of key moments, Samardzija may be able to vouch for it.
The war begged a series of key questions about the EU and its future direction.
By 4am, a series of key results signposted a likely leave victory.
Morgan is the latest in a series of key Pirates players to go down injured.
Yet their skeletons show a series of key transformations that approach those of today's birds.
But a series of key court cases have challenged that notion.
Rhee has been the beneficiary of a series of key developments.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com