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"They are seeing a sequential uptake in January," said Andrew J. Neff, an analyst with Bear , Stearns
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At the same time, competitive pressure is only a necessary condition for sequential uptake to evolve, not a sufficient one.
The table, shows a trend for a higher probability of sequential uptake evolving in the case of extreme limitation than in the case of moderate limitation.
It can also be seen directly from the parameters whether or not a solution has regulated sequential uptake or not.
Indeed, we could only find a single case of regulated sequential uptake for the moderately limited scenario and no case for the unlimited case.
More importantly, our artificial evolution simulations show that sequential uptake is only a secondary adaptation to competition in a dual nutrient environment.
To understand this we plotted the fitness as a function of the phosphorylation rate constant d R in Fig. 8 a using a solution that had evolved to regulated sequential uptake.
As a result, we find that, indeed, sequential uptake of nutrients emerges if there is competition for nutrients and the metabolism/uptake system is capacity limited.
Sequential uptake of nutrient is only a secondary effect that evolves once the potential for speed increase has been exhausted.
However, unless the limitation of uptake is strong this sequential uptake is not regulated but merely a consequence of differing uptake speeds for the two nutrients.
However, a closer inspection of the results reveals that the nature of the sequential uptake in the extremely limited and in the other two cases is fundamentally different.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com