The phrase "a sequential reduction in" is correct and usable in written English.
It can be used when describing a process or trend that involves a series of decreases or diminutions over time or in stages.
Example: "The study observed a sequential reduction in the population of the species over the last decade."
Alternatives: "a gradual decrease in" or "a stepwise decline in".
Figure 9 A illustrates a sequential reduction in the position of the fitted peak of UEA binding untreated pPGM and pPGM treated with 40 and 100 U of fucosidase (48, 41, and 25 nm, respectively).
For PER, TIM and CRY2, we find a consistently smaller peak-to-trough amplitude in the DD compared to LD conditions, a consistent reduction in the JTK_CYCLE algorithm determination of amplitude [ 44], and a sequential reduction in amplitude between the first and second cycle in DD that is not apparent between cycles in LD conditions (Additional file 5).
Similar observations were obtained in a pig model of ARDS induced by oleic acid injection, in which Lambermont and coworkers [ 11] measured functional residual capacity, statistic pulmonary compliance and PaO2 during a sequential reduction in PEEP from high to low levels.
However, previous studies have found that gait freezing episodes are commonly preceded by a sequential reduction in step length a deficit that would account for the increased step length variability in our PD-FOG patients (Nieuwboer et al., 2001; Chee et al., 2009).
In the case of forming alloy nanoparticles, a simultaneous reduction process should be followed, whereas in the case of core shell structures a sequential reduction protocol is essential.
In all patients, EELV decreased significantly corresponding to the sequential reduction in PEEP, whereas the PaO2/FiO2 ratio remained unchanged.
In addition, the treatment with antidiabetic agents, including glucagon-like peptide-1 (GLP-1) receptor agonists, exendin-4, and liraglutide, which are approved for the treatment of T2DM, has been shown to facilitate insulin signaling and sequential reductions in the endogenous levels of A β in the brain and prevent hippocampal neuronal death [ 80].
In the 11 patients who showed sequential reductions in Ki-67 throughout the study period, nine (82%) achieved a clinical response (p = 0.019).
Eleven patients demonstrated sequential reductions in Ki-67 LI throughout the two study periods, and four patients showed sequential increases during therapy.
Indeed, use of increasingly prolonged cut-offs of ≥12, ≥18 and ≥24 weeks was associated with sequential reductions in the numbers of patients that would require tracing.
Rather, there is growing evidence for increased aggressiveness and adaptation by pathogen isolates to partially resistant host lines and thus sequential reductions in the disease control benefit gained from such resistance.
