As a result, the generation of a recombinant PlAMV expression system resulted in a duplicated CP promoter sequence that is much longer than that generated for other potexviruses.
In other cases of gene deletion, genes have been removed and replaced with non-coding sequence that is much higher in AT-content than occurs in the coding regions.
One subject, IU-BAL3, had one lung sequence that was much more diverged from the MRCA than any other sequence from that subject and was also very diverse compared to the other lung sequences.
We perform many tasks in sequence that are much more difficult than the adding of two rows of numbers in parallel.
Through a combination of experimental work and rigorous computational analysis, we show that L. kluyveri ARSs require a sequence that is similar but much longer than the ARS Consensus Sequence well defined in Saccharomyces cerevisiae.
When comparing all mature miRNA arms annotated in TargetScan Human 7, we noticed that miRNAs in highly conserved miRNA seed families contained 6mer seed sequences that were much less toxic in our screen than seeds in poorly conserved miRNAs (Fig. 6a, left panel and Supplementary Fig. 7a).
Indeed, the Dayhoff, JTT, WAG and rtREV models were all trained on sequences that are much more heterogeneous, gearing them towards long-range evolutionary homologies.
It is noteworthy that trnL 1 and trnL 2 share identical sequences that are much longer than expected by chance in all of these five blood-sucking lice.
This is the result of building substitution matrices on libraries of sequences that are much more highly diverged than those within mammalian proteomes.
Most past studies of the HIV-1 frameshift domain, including NMR analyses that tested the two-helix model, used HIV-1 sequences that were much shorter than the 140-nt region that we show here, which constitutes the full frameshift domain.
To maximise the reliability of their method, and keep costs down, they avoided the need to create very long sequences of code – something that is much more expensive than creating lots of short chunks of DNA.
