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Our results provide evidence that local bidimensional engagement of TCR/CD3 specifically triggers intense T cell mechanical activity consisting in a sequence of pushing and pulling forces against the model APC.
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The interface changes include a menu that now puts your selected watchface at the end of a sequence of pushes of the back button no matter where you are, and the up and down buttons on the right-hand side now switch between watch faces, so you don't have to dig through a menu to find them.
We show that upon contact with a model APC coated with antibodies towards TCR-CD3, after a short latency, the T cell developed a timed sequence of pushing and pulling forces against its target.
We demonstrate here that upon engagement of TCR alone, T cells generate a reproducible sequence of pushing and pulling forces displaying characteristic cell protrusion growth velocity, force loading rate and duration.
For the sequence task, visual cues of '123, 321, 213' numbers denote a random sequencing of pushing three buttons with their index, third and fourth fingers on buttons with their dominant hand.
We observed the same qualitative response, i.e. a sequence of latency- pushing- and pulling- phase, ending with the anti-CD3 grafted microbead engulfment.
There is a sequence of Homer trying to push the trampoline off a cliff, but once pushes it over the edge and it falls down, it lands on a pillar of rock and bounces back up.
A sequence-of-tenses problem.
The researchers first scanned a group of seven subjects while they learned a task that required them to push a sequence of computer keys.
To take those visions, won at such cost by artists pushing themselves to the edge of madness and beyond, to a sequence of stereotyped colours and mannerisms, programmed into an app, is to parody, mock and insult real creativity.
Push Up - an attack on corporate life enacted in a sequence of cunning dialogues - suggests it's a rehearsal for a larger work.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com