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It is hypothesized that in individuals with multiple chemical sensitivity (MCS), a sensitization process has occurred that is akin to behavioral sensitization and kindling observed in rodents.
Results: A sensitization to thimerosal was observed in 57 patients.
Only during the bout but not outside, a sensitization of pain processing was observed.
Two days later, all groups received a sensitization challenge test with 2.0 mg/kg apomorphine.
In contrast, flat aggregates presumably consisting of monolayers of 1-1 OHSQ molecules, had a sensitization maximum around 680 nm.
Discretely, in case, of P. aeruginosa less inhibition was observed with a sensitization reaction around the AgNPs loaded wells.
Similar observations were made in a sensitization campaign (Casilino study) on unrecognized migraine that was conducted in Italy in 2003 [16].
CTL activation requires a sensitization phase, in which unprimed T cells interact with antigen-presenting cells (APCs) to become activated lymphocytes.
Recently, several studies on the nociceptive blink reflex have shown a sensitization phenomenon of the trigeminal pathways in migraine patients during the attack [17 19].
The concentration of 2 mM kynurenate is frequently used; a sensitization of capsaicin-induced release observed at 20 mM occurs probably through a different target.
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Our in vitro combination studies demonstrated a sensitization of DMC1-depleted cells to IR with only a modest increase in apoptosis; therefore, drugs targeting other survival pathways may enhance the benefit of targeting DMC1, establishing a synthetically lethal combination.
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