The phrase "a seminal factor" is correct and usable in written English.
It can be used to describe an important or influential element that plays a significant role in a particular situation or outcome.
Example: "The introduction of the internet was a seminal factor in transforming global communication."
Alternatives: "a crucial element" or "a pivotal factor".
In none of these examples was increased pathogenicity to humans an apparent seminal factor in the epidemics.
For both the reference group and all women, the negative association between the seminal factor PSA and L. crispatus was confirmed, as well as a reduced Lactobacillus genus concentration by about one log.
Seminal factors are diluted, and sperm are exposed to a comparably acidic environment, which can reach pH values below 4 due to lactic acid production by native vaginal microflora.
It is possible that seminal factors, when present at high concentrations, prevent interactions between HPV16 and sperm.
Both the absence of seminal factors and low pH may affect the propensity of sperm cells to associate with HPV16.
To remove soluble seminal factors, native semen was diluted 1∶10 with reaction buffer (see below) at the desired pH and incubated for 10 min at 37°C.
Our study extends these observations in two important ways: it shows that HPV16 has two distinct binding sites along the equator of the sperm heads, and moreover, that virus association to these domains is more efficient in neutral conditions and after removal of soluble seminal factors.
Although cell lines have played a seminal role in describing how transcription factors interact with the genome [ 1, 2, 9- 13], transcription factor characterization in primary tissues is a critical next step.
The validation of KRAS mutations as a negative marker of response to anti-epidermal growth factor receptor (EGFR) antibodies has meant a seminal advance towards treatment individualisation of colorectal cancer (CRC) patients.
In 2004, a seminal study with this technique showed that CTC count was an independent prognostic factor for both progression-free (PFS) and overall (OS) survival in metastatic (M1) breast cancer patients [ 1].
