The phrase "a selective small" is not correct in English and does not convey a clear meaning.
It seems to be an attempt to describe a specific subset or group, but the combination of "selective" and "small" is awkward and unclear.
Example: "We are looking for a selective small group of participants for our study."
Alternatives: "a carefully chosen small" or "a specific small".
Picaud, S. et al. Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy.
Bowers, E. M. et al. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor.
Holland, S.J. et al. R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Our results introduce opportunities for new combination strategies using a selective small molecule PI3Kγ inhibitor, such as IPI-549, to overcome resistance to ICB in patients with high levels of suppressive myeloid cell infiltration in tumours.
A selective small molecule inhibitor of FphB effectively reduced infectivity in vivo, suggesting that it may be a viable therapeutic target for the treatment or management of Staphylococcus infections.
A selective small molecular GPR-119 agonist, PSN632408, can reduce food intake and body weight gain in rodents through increasing intracellular cAMP levels (Overton et al., 2006).
As a selective small-molecule inhibitor of BET bromodomains, JQ1 transcriptionally downregulates Myc itself and its target genes31.
We report that TG101348, a selective small-molecule inhibitor of JAK2 with an in vitro IC50 of approximately 3 nM, shows therapeutic efficacy in a murine model of myeloproliferative disease induced by the JAK2V617F mutation.
SRT2379 is a selective small-molecule activator of the NAD+-dependent deacetylase, Sirtuin 1 (SIRT1), which has broad anti-inflammatory effects in cell cultures and rodents.
Toward this objective, we explored the spermatogenic effects of a selective small-molecule inhibitor (JQ1) of the bromodomain and extraterminal (BET) subfamily of epigenetic reader proteins.
Gefitinib, a selective small-molecule EGFR tyrosine kinase inhibitor, is widely used as a second- or third-line therapy for the treatment of patients with advanced non-small cell lung cancer (NSCLC) who failed to respond to standard chemotherapy [ 7].
