CAR-T cells tumor sculpting exerts a selective pressure involving the selection of antigen-negative cells over time.
To what extent do you believe natural selection is continuing to act as a selective pressure within the human species?
Besides, plasmid loss was observed along process time indicating a selective pressure against plasmid-bearing cells.
And when a selective pressure like chemotherapy is applied to a cancer, resistant mutants escape that pressure.
These results suggest that antigen stimulation may provide survival signals to tumor cells and that there is a selective pressure to preserve antigen recognition as the tumor evolves.
Adding a selective pressure to minimize connection costs leads to the evolution of modular networks that quickly adapt to new environments.
It is rapid, with diversification taking only a few hours, and it does not require application of a selective pressure throughout the process.
Metals also can exert a selective pressure on the organisms, resulting in microbial populations with higher tolerance to metals.
Improper and extensive usage of antibiotics results in a selective pressure supporting the rise of antibiotic-resistant microbes.
Our results suggest that regulatory control can provide a selective pressure that drives operons together in the course of evolution.
Each species exerts a selective pressure on the other, so they evolve together (Van den Bergh and Stagl 2004).
