Exact(1)
A selected regulator CIITA was shown to regulate two classes of antigens MHC I and II in DLBCL (Cycon et al., 2009).
Similar(59)
To analyze the effects of a variety of cellular growth rate regulators we employed the same primer extension analysis described above and compared the amount of rsd promoter-derived transcripts from wild-type strains and strains with mutations in the genes for a number of selected regulators, which had been transformed with the rsd promoter vector prsd-up-cat.
The active ERK concentration at steady state was measured after treatment with the model-selected concentrations of regulators to reflect the influence of selected regulators [ 14].
A bidirectional BlastP analysis was performed using as query the amino acid sequences of 48 selected regulators.
Overlap among these selected regulators and their targets was found, in which 20 to 28 target genes were shared; consequently, multiple genes in the IGVH signature were co-regulated by several TFs (Additional file 1: Table S2).> Expression profiles were tested to evaluate their relationship with outcome using the GSE22762 (n = 107) and GSE39671 (n = 130) datasets.
We extend the Bayesian model averaging (BMA) variable selection method to select regulators in the regression framework.
C1 Scramble to Select Regulators Amidst a political firestorm, the chairman of the Securities and Exchange Commission postponed a trip to Europe to search for candidates to fill the new board that will oversee the accounting profession.
Technically, the optimization problem solved for selecting regulators of gene g is the following penalized regression problem β ^ (g ) = arg min β (g ) ∈ ℝ | R | 1 2 ‖ X g − X R β (g ) ‖ 2 + λ ∑ k = 1 K ‖ (β ℋ k (g ) ) + ‖ 2 + ‖ (β ℋ k (g ) ) − ‖ 2, with X g the expression profile of gene g and X R the expression profiles of the regulators.
Although it is known that USA300 has altered regulation of selected global regulators and virulence genes compared with USA400, it is not known whether there are global differences in the transcription profiles between USA300 and USA400.
Thus, active TFs have a stronger prior of being selected as regulators by DREM 2.0 (see Additional file 2).
The list of all genes sorted out as putatively regulated by the selected transcriptional regulators is reported in Additional file 6.
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