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A secondary (sensitivity) analysis was undertaken using participants with complete data on the relevant two rounds for each analysis of temporal change.
A secondary sensitivity analysis was done to determine the impact of including only study completers for the primary outcome BPI Pain Severity and Interference scores instead of using the more conservative method of last observation carried forward.
59 To determine whether the results would differ if missing data were replaced using the last observation we will undertake a secondary sensitivity analysis using a last observation carried forward method.
A secondary sensitivity analysis, excluding those patients with a change in primary residence in the claims data during the study period, was also performed to determine whether persons who had recently moved affected incidence rates.
However, given the popularity of simple data imputation methods [ 105, 107] we will undertake a secondary sensitivity analysis to determine whether the results would differ if missing data were replaced using the last observation carried forward method.
However, because this was a relatively large study, and the appropriateness of excluding elective neurosurgical patients is somewhat debatable, these results were incorporated into a secondary sensitivity analysis, from which the redundant data from the two other trials were removed [ 63, 64].
Similar(53)
In a secondary model (sensitivity analysis), we used VES-12 (which excludes age from calculation of the VES score) as the outcome 23 and included age as a predictor.
This approach can be used to complement the more usual random effects analysis as a secondary or sensitivity analysis and we consider this approach more satisfactory than performing analyses that simply omit any outliers although these analyses may also be performed if desired.
It is important to note however, that these secondary sensitivity analyses are data-driven, and are presented as a supplement to the primary analyses that include all nine SNPs.
The primary sensitivity of arrival times is to changes of the water depth overlying the source region, with secondary sensitivity to the travel distance perturbation.
Model results for secondary sensitivity analysis of VES-12 score demonstrated similar results.
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