The phrase "a secondary pathway" is correct and usable in written English.
It can be used to refer to an alternative route or method in various contexts, such as biology, transportation, or problem-solving.
Example: "In addition to the main route, there is a secondary pathway that can be used to reach the destination more quickly."
Alternatives: "an alternative route" or "a backup path".
These physical properties have been optimised to realise a secondary pathway to puncture-repair as a result of swelling on water contact.
Taken together, these data point towards a secondary pathway, involving PKC, and independent from the calcineurin pathway, which regulates RCAN1.4.
There is also evidence of a secondary pathway of phospholipase C activation for the homologous LHCGR [30] and FSHR [31], [32].
The TSHR is an important key-player in endocrine signaling cascades and was recently demonstrated to be of high physiological importance for thyroid function by causing stimulation of phospholipase C via Gq/11-activation through a secondary pathway [28], [29].
HIF signaling therefore constitutes a secondary pathway affecting gene expression in hypertrophic remodeling.
A secondary pathway is mediated by Atg6/beclin-1, which forms a complex with Vps34, the class III PI3K.
For this reason, we used this model to determine whether Ras, Raf and/or Pi3k signaling constituted a preferred secondary pathway with MYCN deregulation.
These data support that activated Ras-mediated signal transduction does not constitute a preferred secondary pathway for neuroblastic tumors in concert with deregulated MYCN.
In physiologic conditions, this may function not only to recruit neutrophils to joint spaces and exacerbate the inflammatory conditions but also to act as a complementary secondary pathway for continuous osteoclast differentiation leading to bone loss.
Further, despite compelling evidence for MYC and RAS cooperation in vitro and in vivo to promote tumourigenesis, activation of RAS signal transduction does not constitute a preferred secondary pathway in neuroblastomas with MYCN deregulation in either human tumors or murine models.
For example, an important secondary pathway that branches from glycolysis is the pentose phosphate pathway (PPP), which uses glucose-6-phosphate in reactions that ultimately produce both NADPH and ribose-5-phosphate (R5P).
